Detalhe da pesquisa
1.
Testing the feasibility of targeting a conserved region on the S2 domain of the SARS-CoV-2 spike protein.
Biophys J
; 123(8): 992-1005, 2024 Apr 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38491772
2.
Cyclization Scaffolding for Improved Vaccine Immunogen Stability: Application to Tau Protein in Alzheimer's Disease.
J Chem Inf Model
; 64(6): 2035-2044, 2024 Mar 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-38427576
3.
PROTHON: A Local Order Parameter-Based Method for Efficient Comparison of Protein Ensembles.
J Chem Inf Model
; 63(11): 3453-3461, 2023 06 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37178169
4.
De Novo Design of a ß-Helix Tau Protein Scaffold: An Oligomer-Selective Vaccine Immunogen Candidate for Alzheimer's Disease.
ACS Chem Neurosci
; 14(15): 2603-2617, 2023 08 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-37458595
5.
Targeting RACK1 to alleviate TDP-43 and FUS proteinopathy-mediated suppression of protein translation and neurodegeneration.
Acta Neuropathol Commun
; 11(1): 200, 2023 Dec 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-38111057
6.
Ensemble Generation for Linear and Cyclic Peptides Using a Reservoir Replica Exchange Molecular Dynamics Implementation in GROMACS.
J Phys Chem B
; 126(49): 10384-10399, 2022 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36410027
7.
First Principles Calculation of Protein-Protein Dimer Affinities of ALS-Associated SOD1 Mutants.
Front Mol Biosci
; 9: 845013, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35402516
8.
Optimizing Epitope Conformational Ensembles Using α-Synuclein Cyclic Peptide "Glycindel" Scaffolds: A Customized Immunogen Method for Generating Oligomer-Selective Antibodies for Parkinson's Disease.
ACS Chem Neurosci
; 13(15): 2261-2280, 2022 08 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35840132
9.
Rational Generation of Monoclonal Antibodies Selective for Pathogenic Forms of Alpha-Synuclein.
Biomedicines
; 10(9)2022 Sep 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36140270